彭晓丽
基本信息
彭晓丽，女，1982年生于重庆潼南，博士，副教授，博士生导师
工作经历
2000.9-2004.6，西北农林科技大学，园艺学院，园产品贮藏加工，农学学士
2004.9-2007.6，西北农林科技大学，园艺学院，园产品贮藏加工，农学硕士
2007.9-2010.6，中国农业大学，食品科学与营养工程学院，食品科学，工学博士
2010.7-2014.12， 西北农林科技大学，食品科学与工程学院，讲师
2015.1-今，西北农林科技大学，食品科学与工程学院，副教授
科学研究
主要从事食品分子毒理与营养研究，包括食品安全危害因子在实验动物、人细胞水平对细胞凋亡、线粒体功能、蛋白组学、基因表达谱、细胞信号转导、氧化胁迫等方面的影响；食品营养因子对食品安全危害物损伤机体的营养干预研究；采用基因沉默及过表达手段挖掘关键蛋白分子在食品危害因子、食品营养因子作用过程中的调控作用研究。
主持项目如下：
1.陕西省重点研发计划项目一般项目（2020NY-106）,2020-2022
2.国家自然科学基金面上项目（31571928），2016-2019
3.北京食品营养与人类健康高精尖创新中心开放基金，2018-2019.
4.国家自然科学基金青年项目（31201286），2013-2015.
5.西北农林科技大学基本科研业务费青年培育专项基金，2015.
6.西北农林科技大学基本科研业务费（2014YB021），2014-2016.
7.西北农林科技大学博士科研启动基金（2010BSJJ053），2011-2013.
主要研究成果如下：
1. Chengni Jin, Yujie Zhong, Jiahui Han, Jiachang Zhu, Qi Liu, Dianjun Sun, Xiaodong Xia, Xiaoli Peng*, 3-MCPD induces nephrotoxicity through the LKB1/AMPK signaling pathway, mitochondrial fission, and apoptosis in Sprague-Dawley rats and human embryonic kidney 293 (HEK293) cells, Food and Chemical Toxicology, 2021，154：112350-112358. IF="6.023
2. Yujie Zhong, Chengni Jin, Jiahui Han, Jiachang Zhu, Qi Liu, Dianjun Sun, Xiaodong Xia, Yu Zhang*, Xiaoli Peng*, Diosgenin protects against kidney injury and mitochondrial apoptosis induced by 3-MCPD through the regulation of ER stress, calcium homeostasis and Bcl2 expression, Molecular Nutrition and Food Research, 2021, 2001202:1-11. IF="5.914
3.Yujie Zhong, Chengni Jin, Jiahui Han, Qi Liu, Jiachang Zhu, Dianjun Sun, Xiaodong Xia, Xiaoli Peng*, Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis, Cell Biology and Toxicology, 2021, 5: 1-15.IF="6.023
4. Jiahui Han#, Chengni Jin#, Yujie Zhong, Jiachang Zhu, Qi Liu, Dianjun Sun, Jiayu Feng, Xiaodong Xia, Xiaoli Peng*, Involvement of NADPH oxidase in patulin-induced oxidative damage and cytoxicity in HEK293 cells, Food and Chemical Toxicology, 2021, 150: 112055- 112064.IF="6.023
5. Jiahui Han#, Yujie Zhong#, Chengni Jin, Ruilin Luo, Manying Xia, Yushu He, Jiayu Liu, Xiaoli Peng*, Apocynin attenuates patulin-induced cytotoxicity through reduction of oxidation stress and apoptosis in HEK293 cells, World Mycotoxin Journal, 2021,14 (1): 1-10.IF="3.353
6. Chengni Jin#, Yujie Zhong, Jiahui Han, Jiachang Zhu, Qi Liu, Dianjun Sun, Xiaodong Xia, Xiaoli Peng*, Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-MCPD in HEK293 cells, Food and Chemical Toxicology, 2020, 145: 111740. IF="4.676."
7. Xin Miao#, Chengni Jin#, Yujie Zhong, Jiayu Feng, Chunhong Yan, Xiaodong Xia, Yu Zhang*, Xiaolii Peng*, Data Independent Acquisition-Based Quantitative Proteomic Analysis Reveals the Protection Effect of Apigenin on Palmitate Induced Lipotoxicity in HAEC cells, Journal of Agricultural and Food Chemistry, 2020. IF="4.192
8. Chengni Jin#, Xin Miao, Yujie Zhong, Jiahui Han, Qi Liu, Jiachang Zhu, Xiaodong Xia, Xiaoli Peng*, The enoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy, Food Function, 2020,11:7456-7467. IF="4.171
9. Pengfei Zhang#, Xin Miao, Luhong Zhou, Baozhong Cui, Jie Zhang, Xuebin Xu, Congming Wu, Xiaoli Peng*, Xin Wang*, Characterization of oxacilln-susceptible mecA-positive Staphylococcus aureus from food poisoning outbreaks and retail foods in China, Foodborne Pathogens and Disease, 2020,17:728-735. IF="2.601
10. Xiaorui Wang#, Chengni Jin#, Yujie Zhong, Xuan Li, Jiahui Han, Wei Xue, Peng Wu, Xiaodong Xia*, Xiaoli Peng*, Glutathione reduction of patulin-evoked cytotoxicity in HEK293 cells by the prevention of oxidative damage and the mitochondrial apoptotic pathway, Journal of Agricultural and Food Chemistry, 2018, 66: 7775-7783. IF="3.412
11. Yujie Zhong#, Chengni Jin, Xiaorui Wang, Xuan Li, Jiahui Han, Wei Xue, Peng Wa, Xiaodong Xia* and Xiaoli Peng*, Protective effects of apigenin against 3-MCPD-induced renal injury in rat, Chemico-biological interaction, 2018, 296,9-17. IF="3.296
12. Yujie Zhong#, Chengni Jin, Xiaorui Wang, Xuan Li, Jiahui Han, Wei Xue, Peng Wu, Xiaodong Xia*, Xiaoli Peng*, The effect of apigenin on 3- chloro-1,2-propanediol induced renal injury and mitochondrial fission and fusion in rats, Food Science, 2018, 5, 15.EI
13. Yujie Zhong#, Chengni Jin#, Jing Gan, Xiaorui Wang, Zhenqiang Shi, Xiaodong Xia*, Xiaoli Peng*, Apigenin attenuates patulin-induced apoptosis in HEK293 cells by modulation ROS-mediated mitochondrial dysfunction and caspase signal pathway, Toxicon, 2017, 137: 106-113 IF="2.352
14. Xiaoli Peng#, Jing Gan#, Qian Wang#, Zhenqiang Shi, Xiaodong Xia*, 3-Monochloro-1,2-propanediol (3-MCPD) induces apoptosis via mitochondrial oxidative phosphorylation system impairment and the caspase cascade pathway, Toxicology, 2016,372:1-11.IF="3.817
15. Baigang Zhang#, Xiaoli Peng*, Guanghui Li, Xiaodong Xia*, Oxidative stress is involved in Patulin induced apoptosis in HEK293 cells, Toxicon, 2015, 94: 1-7. IF="2.581
16. Xiaoli Peng#, Jingpeng Yang, Pengle Cui, Yu Fu, Qiang Zhang, Xiaodong Xia*, Influence of allicin on quality and volatile compounds of fresh-cut stem lettuce during cold storage, LWT-Food Science and Technology, 2015, 60 (1): 300-307. IF="2.468
17. Xiaoli Peng#, Ren L, Rong Zou, Jun Chen, Qiang Z, Pengle Cui, Fuli Chen, Yu Fu, Jingpeng Yang, Xiaodong Xia*. Allicin inhibits microbial growth and oxidative browning of fresh-cut lettuce (Lactuca sativa) during refrigerated storage. Food and Bioprocess Technology, 2014，7：1597-1605. IF="3.126"
18. Yan Wang#, Xiao-Li Peng#, Wentao Xu, YunBo Luo, Kunlun Huang*. Transcript and protein profiling analysis of OTA-induced cell death reveals the regulation of the toxicity response process in Arabidopsis thaliana. Journal of Experimental Botany, 2012, 63 (5): 2171-2187. IF="5.794"
19. Xiao-Li Peng#, Wen-Tao Xu, Kun-Lun Huang, Yun-Bo Luo*, Mycotoxin ochratoxin A-induced cell death and changes in oxidative metabolism of Arabidopsis thaliana. Plant Cell Report, 2010, 29: 153-161. IF="2.30120.
20. Wen-Tao Xu#, Xiao-Li Peng#, Yun-Bo Luo, Kun-Lun Huang*, Physiological and biochemical responses of grapefruit seed extract dip on ‘Redglobe’ grape. LWT-Food Science and technology, 2009, 42:471-476. IF="2.114
21. 甘婧#，张百刚，师振强，钟玉杰，王晓瑞，晋程妮，夏效东，彭晓丽*，基因表达谱技术分析棒曲霉毒素肾细胞毒性的机制，现代食品科技，2017, 33, 6：38-44
联系方式
通讯地址：陕西省杨凌区西北农林科技大学食品科学与工程学院
邮编：712100
联系电话：15319729682
Email：pxlpxh@163.com