单忠国
个人信息
单忠国,男,1984年12月,博士,讲师,硕士生导师。
学习工作经历
2018-09至现在,西北农林科技大学,食品科学与工程学院,讲师
2017-03至2018-06,美国罗德岛大学,药学院,博士后
2016-07至2017-03,中国科学院,天津工业生物技术研究所,助理研究员
2011-09至2015-12,厦门大学,环境与生态学院,博士
2008-09至2011-06,辽宁师范大学,生命科学学院,硕士
2004-09至2008-06,辽宁师范大学,生命科学学院,学士
科学研究
主要从事天然抗菌物质的制备及其在食品和水产养殖领域的应用开发研究工作。
主持相关研究
1.大连佳泽海珍品育苗场,校企合作横向课题项目,K4030220475,基于天然抗菌物质的鲍鱼饲料添加剂的研发;
2.陕西省青年基金,2020JQ-266,新型食品添加剂抑制产气荚膜梭菌芽孢萌发的分子机制研究;
3.博士后科学基金面上项目,2019M653766,新型抗菌肽对食源性致病菌芽孢的杀灭机制研究;
4.西北农林科技大学博士科研启动基金,Z1090219012,产气荚膜梭菌耐环境压力分子机制研究。
目前以第一作者或通讯作者在Aquaculture,Front. Microbiol,Fish Shellfish Immunol,Toxicol. Appl. Pharmacol等主流学术期刊上发表SCI论文7篇,授权发明专利1项。
1. Zhongguo Shan*; Meilin Wang; ShiYao Zhao; Xiner Xie; Dongbo Yang; XinRui Hu; Weidong Liu*; Cinnamaldehyde exerts prophylactic and therapeutic effects against Vibrio anguillarum infection in Yesso scallop ( Patinopecten yessoensis ) by its direct antimicrobial activity and positive effect on the innate immunity, Aquaculture , 2021, 538: 736588.
2. Zhongguo Shan; Ning Guan; Yanpeng Yang; Tong Jin; Xiaodong Xia*; Weidong Liu*; Elucidation of the potential mechanism of punicalagin for conferring disease resistance in Yesso scallops against Vibrio anguillarum infection, Aquaculture , 2021, 533: 736109
3. Zhongguo Shan; Yanpeng Yang; Ning Guan; Xiaodong Xia*; Weidong Liu *; NKL-24: A novel antimicrobial peptide derived from zebrafish NK-lysin that inhibits bacterial growth and enhances resistance against Vibrio parahaemolyticus infection in Yesso scallop, Patinopecten yessoensis , Fish & Shellfish Immunology , 2020, 106: 431-440.
4. Zhongguo Shan; Zhengxi Wei; Shaikh Zahir A*; Suppression of ferroportin expression by cadmium stimulates proliferation, EMT, and migration in triple-negative breast cancer cells, Toxicology and Applied Pharmacology , 2018, 356: 36-43.
5. Zhongguo Shan; Kexin Zhu; Fangyi Chen; Jie Liu; Bei Chen; Kun Qiao; Hui Peng; Kejian Wang*; In vivo activity and the transcriptional regulatory mechanism of the antimicrobial peptide SpHyastatin in Scylla paramamosain , Fish & Shellfish Immunology , 2016, 59: 155-165.
6. Zhongguo Shan; Kexin Zhu; Hui Peng; Bei Chen; Jie Liu; Fangyi Chen; Xiaowan Ma; Shuping Wang; Kun Qiao; Kejian Wang*; The new antimicrobial peptide SpHyastatin from the mud crab Scylla paramamosain with multiple antimicrobial mechanisms and high effect on bacterial infection, Frontiers in Microbiology , 2016, 7: 1140.
7. Zhongguo Shan, Hongjun Li, Xiangbo Bao, Chongbo He, Henan Yu, Weidong Liu*, Lin Hou**, Dan Zhu, Lijun Sun, Bao Zhu, Yunfeng Li. A selenium-dependent glutathione peroxidase in the Japanese scallop, Mizuhopecten yessoensis : cDNA cloning, promoter sequence analysis and mRNA expression. Comparative Biochemistry and Physiology, Part B . 2011, 159(1):1-9.
荣誉获奖
1. 2021年国家级大学生创新创业训练计划项目立项(指导教师);
2. 2021年全国大学生生命科学竞赛(创新创业类)三等奖(指导教师)。
联系方式
通讯地址:陕西杨凌西农路22号 西北农林科技大学食品科学与工程学院A626
邮编:712100
Email:shanzhongguo@163.com
QQ:398572069