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庞卫军

发布日期:2021-07-07   阅读次数:

       一、个人简历

  庞卫军,男,九三学社社员,教授,博士生导师。2007年入选西北农林科技大学“青年学术骨干支持计划”;2008年为西北农林科技大学“科技工作先进个人”;2007年、2011年、2013年、2015年和2018年为动物科技学院“优秀教师”; 2011年被陕西省农业厅聘为“生猪产业技术体系育种岗位专家”;2017年陕西省三区人才;2018年陕西省科技特派员;2010.2~2011.2 在美国贝勒医学院(Baylor College of Medicine)做访问学者,从事动物脂肪沉积领域的研究。主持国家自然基金、国家重点研发计划、973计划、陕西省重大产业链和陕西省自然基金等多项国家及省部级项目,围绕肌肉生物学与猪遗传改良开展科研工作。

  二、社会兼职

  中国细胞生物学会、遗传学会和畜牧兽医学会员。是20余种SCI期刊:《 Nature Protocols 》、《 Stem Cells 》、《 Journal of Biological Chemistry 》、《 Molecular Nutrition and Food Research 》、《 Journal of Agricultural and Food Chem i stry 》、《 Cell Proliferation 》、《 Journal of Cellular and Molecular Medicine 》、《 J ournal of C ellular P hysiology 》、《 Journal of Cellular Biochemistry 》、《 Journal of Molecular Endocrinology 》、《 BMC Genomics 》、《 Cytokine》、 《 Molecular and Cellular Biochemistry 》、 《Lipids 》、《 Pharmacological Research 》、《 Biomedicine and  Pharmacotherapy 》、《 Theriogenology 》、《 Fish and Shellfish Immunology 》、《 Animal Reproduction Science 》、《 Scientific Reports 》和《 Gene 》等的审稿专家。

  三、研究兴趣

  1. 脂肪沉积及其分子调控机制

  2. 肌肉发育及其分子调控机制

  3. 猪胴体和肉质性状的精准测定技术

  4. 猪人工授精技术

  5. 智能化养猪技术

  四、发表的论文

  围绕肌肉生物学与猪遗传改良,针对猪脂肪沉积与肌肉发育、猪分子育种以及智能化养猪技术领域开展研究工作,在《 RNA Biology 》、《 Journal of Biological Chemistry 》、《 BBA-Molecular and Cell Biology of Lipids 》、《 Cells 》、《 Journal of Agricultural and Food Chem i stry 》、《 M ea t Science 》、《 Journal of Cellular Biochemistry 》、《 Experimental Cell Research 》、《 J ournal of Anim al Science 》、《 Animal Genetics 》、《 Animal 》、《 Theriogenology 》、《 D evelopmental and C omparative I mmunology 》、 《 Gene 》、《 遗传学报 》、《 中国农业科学 》和《 畜牧兽医学报 》等期刊发表科研论文100余篇,其中SCI论文50余篇, 2篇SCI论文( RNA Biology , 2017, 14(3), IF=5.477和 J ournal of C ellular B iochemistry , 2013, 114(11), IF="3.448)以封面文章发表。

  近5年以第一或通讯作者发表的主要学术论文(*为通讯作者):

  1. Cai R, Tang GR, Zhang Q, Yong WL, Zhang WR, Xiao JY, Wei CS, He C, Yang GS, Pang WJ*. A Novel lnc-RNA, Named lnc-ORA, Is Identified by RNA-Seq Analysis, and Its Knockdown Inhibits Adipogenesis by Regulating the PI3K/AKT/mTOR Signaling Pathway. Cells , 2019, 8(5), pii: E477. (IF=5.656,中科院Ⅱ区)

  2. Qin J, Sun YM, Liu SG, Zhao R, Zhang QY, Pang WJ*. MicroRNA-323-3p promotes myogenesis by targeting Smad2. J ournal of C ellular B iochemistry , 2019, online, doi. org/10.1002/jcb.29187. (IF=3.448)

  3. Shaoyong WK, Li Q, Ren ZQ, Wei CS, Chu GY, Dong WZ, Yang GS, Pang WJ*. Evaluation of ε-polylysine as antimicrobial alternative for liquid-stored boar semen. Theriogenology , 2019, 130: 146-156. (IF=2.299, 中科院Ⅱ区)

  4. Chen FF, Wang YQ, Tang GR, Liu SG, Cai R, Gao Y, Sun YM, Yang GS*, Pang WJ*. Differences between porcine longissimus thoracis and semitendinosus intramuscular fat content and the regulation of their preadipocytes during adipogenic differentiation. Meat Science , 2019, 147(1): 116–126. (IF=3.483,中科院Ⅱ区)

  5. Qimuge N, He ZZ, Qin J, Sun YM, Wang XM, Yu TY, Dong WZ, Yang GS, Pang WJ*. Overexpression of DNMT3A promotes proliferation and inhibits differentiation of porcine intramuscular preadipocytes by methylating p21 and PPARg promoters. Gene , 2019, 696: 54–62.

  6. Cai R, Qimuge N, Ma ML, Wang YQ, Tang GR, Zhang Q, Sun YM, Chen XC, Yu TY, Dong WZ, Yang GS, Pang WJ*. MicroRNA-664-5p promotes myoblast proliferation and inhibits myoblast differentiation by targeting serum response factor and Wnt1.  Journal of Biological Chemistry , 2018, 293(50): 19177–19190. (IF=4.106, 中科院Ⅱ区, Top期刊,“双一流”学科群B类期刊)

  7. Sun YM, Chen XC, Qin J, Liu SG, Zhao R, Yu TY, Chu GY, Yang GS*, Pang WJ*. Comparative analysis of long noncoding RNAs expressed during intramuscular adipocytes adipogenesis in fat-type and lean-type Pigs. J ou rnal of Agricultural and Food Chemistry , 2018, 66(45): 12122–12130. (IF=3.571, 中科院Ⅰ区, Top期刊)

  8. Cai R, Sun YM, Sun YM, Naren QMG, Wang GQ, Wang YQ, Chu GY, Yu TY, Yang GS, Pang WJ*. Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation. BBA-Molecular and Cell Biology of Lipids , 2018, 1863(4): 420–432. (IF=4.966, 中科院Ⅱ区)

  9. Chen XC, Sun YM, Cai R, Wang GQ, Shu XY, Pang WJ*. Long noncoding RNA: multiple players in gene expression. BMB Rep orts , 2018, 51(6): 281–290. (IF=3.085)

  10. Gao Y, Qimuge NR, Qin J, Cai R, Li X, Chu GY, Pang WJ*, Yang GS*. Acute and chronic cold exposure differentially affects the browning of porcine white adipose tissue.  Animal , 2018, 12(7):1435–1441. (IF=2.026, 中科院Ⅱ区)

  11. Ma ML, Wang XM, Chen XC, Cai R, Chen FF, Dong WZ, Yang GS, Pang WJ*. MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway. RNA Biology , 2017, 14(3): 347–360. (IF=5.477, 中科院Ⅱ区, Cover story)

  12. Sun YM, Qin J, Liu SG, Cai R, Chen XC, Wang XM, Pang WJ*. PDGFRa regulated by miR-34a and FoxO1 promotes adipogenesis in porcine intramuscular preadipocytes through Erk signaling pathway. I nternational  J ournal   of  M olecular  S ciences , 2017, 18(11): 2424. (IF=3.687)

  13. Lv S, Ma ML, Sun YM, Wang XM, Naren Qimuge, Qin J, Pang WJ*. MicroRNA-129-5p inhibits 3T3-L1 preadipocyte proliferation by targeting G3BP1. Animal Cells and Systems , 2017, 21(4): 269–277.

  14. Wang GQ, Wang Y, Xiong Y, Chen XC, Ma ML, Cai R, Gao Y, Sun YM, Yang GS, Pang WJ*. Sirt1  AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a. Scientific Reports , 2016, 6: 21865. (IF=5.228, Cites: 31)

  15. Wu WJ, Sun YM, Zhao CZ, Zhao C, Chen XC, Wang GQ, Pang WJ*, Yang GS*. Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway.  Acta Biochim ica   et Biophys ica  Sin ica , 2016, 48(6): 509–519. (Cites: 10)

  16. Wang GQ, Zhu L, Ma ML, Chen XC, Gao Y, Yu TY, Yang GS, Pang WJ*. Mulberry 1-Deoxynojirimycin Inhibits Adipogenesis by Repression of the ERK/PPARγ Signaling Pathway in Porcine Intramuscular Adipocytes. Journal of Agricultural and Food Chem i stry , 2015, 63(27): 6212–6220. (IF=3.412, 中科院Ⅰ区, Top期刊, Cites: 12)

  17. Wei N, Wang Y, Xu RX, Wang GQ, Xiong Y, Yang GS, Pang WJ*. PU.1 antisense lncRNA against its mRNA translation promotes adipogenesis in porcine preadipocytes. Animal genetics , 2015, 46(2):133–140. (Cites: 26)

  18. Pang WJ*, Wei N, Wang Y, Xiong Y, Chen FF, Wu WJ, Zhao CZ, Sun SD, Yang GS. Obese and lean porcine difference of FoxO1 and its regulation through C/EBPβ and PI3K/GSK3β signaling pathway. J ournal of Anim al Science , 2014, 92(5): 1968–1979. (中科院Ⅱ区, Top期刊, Cites: 10)

  19. Wei N, Pang WJ*, Wang Y, Xiong Y, Xu RX, Wu WJ, Zhao CZ, Yang GS. Knockdown of PU.1 mRNA and AS lncRNA regulates expression of immune-related genes in zebrafish Danio rerio. D evelopmental and C omparative I mmunology , 2014, 44(2):315–319. (IF=3.705, Top期刊, Cites: 13)

  20. Wang Y, Pang WJ*, Wei N, Xiong Y, Wu WJ, Zhao CZ, Shen QW, Yang GS. Identification, stability and expression of Sirt1 antisense long non-coding RNA.  Gene , 2014, 539(1): 117–124. (Cites: 28)

  21. Pang WJ*, Xiong Y, Wang Y, Tong Q, Yang GS. Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes.  Exp erimental  Cell Res earch , 2013, 319(5): 670–683. (IF=3.329, Cites: 17)

  22. Pang WJ*, Lin LG, Xiong Y, Wei N, Wang Y, Shen QW, Yang GS. Knockdown of PU.1 AS lncRNA inhibits adipogenesis through enhancing PU.1 mRNA translation.  J ournal of C ellular B iochemistry , 2013, 114(11): 2500–2512. (IF=3.368, Cover story, Cites: 47)

  23. Pang WJ*, Wang Y, Wei N, Xu RX, Xiong Y, Wang P, Shen QW, Yang GS. Sirt1 Inhibits Akt2-mediated Porcine Adipogenesis Potentially by Direct Protein-Protein Interaction. PLoS One , 2013, 8(8): e71576. (IF=3.73, Cites: 19)

  24. Xiong Y, Pang WJ*, Wei N, Wang Y, Ren WK, Yang GS. Knockdown of both FoxO1 and C/EBPβ promotes adipogenesis in porcine preadipocytes through feedback regulation. C ell B iology I nternational , 2013, 37(9): 905–916. (Cites: 15)

  五、科研项目

  (一)在研项目

  1. 国家自然基金项目面上项目:GRP78 AS lncRNA调控猪骨骼肌纤维脂质沉积的作用机制(31872979),2019.01–2022.12,59万元,主持;

  2. 国家自然基金项目面上项目:猪肌内脂肪沉积的lncRNA鉴定及其调控机制研究(31572366), 2016.01–2019.12,64万元,主持;

  3. 国家重点研发计划课题:种畜禽重要经济性状精准测定技术研发(2017YFD0502002),2017.07–2020.12,286万元,主持;

  4. 国家重点基础研究发展计划(973计划)项目子课题:Leptin及相关因子调控脂肪发育的分子机制(2015CB943102-3),2015.01–2019.12,90万元,主持;

  5. 陕西省重点研发计划项目:生猪养殖智能化关键技术研发与示范(2018ZDCXL–NY–02–03),2018.01–2020.12,50万元,主持.

  (二)已结题项目

  1. 国家自然基金项目青年项目:Sirt1通过Caspase-3调控猪前体脂肪细胞凋亡的分子机理(30600437),2007.01-2009.12,主持;

  2. 国家重点基础研究发展计划(973计划)项目子课题:机体碳代谢对脂肪沉积和肉品质形成的调控(2012CB124705-3),2012.01-2016.12,主持;

  3. 陕西省自然科学基金项目:长链非编码RNA调控关中黑猪肌内脂肪沉积的作用与分子机理(2015JM3096),2015.01-2016.12,主持;

  4. 陕西省自然科学基金项目:Sirt1调控猪前体脂肪细胞分化的分子机理(2006C112),2006.01-2007.12,主持. 

  六、科研成果

  1. 猪脂肪沉积及其调控机制研究,2016年陕西省科学技术三等奖,1/7;

  2. 猪脂肪细胞增殖与分化调控及其机理研究,2006年陕西省科学技术二等奖,4/9。

  七、培养学生

  指导研究生31名,在读13(博士生3名,硕士生10名);毕业18名。其中,获得国家奖学金、校优秀硕士毕业论文和优秀研究生等荣誉。指导本科生国家级和校级“科创项目”多项,培养本科毕业生30余名,其中多名获得优秀毕业论文奖。

  八、联系方式

  地址:陕西杨凌西农路22号, 西北农林科技大学动物科技学院大楼,邮编 712100

  E-mail: pwj1226@nwafu.edu.cn

  QQ: 546570320

  手机号:13991377993